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GLP-1 therapy may be most relevant when lipedema overlaps with other metabolic or weight-related concerns, such as: Obesity or significant weight gain Prediabetes or insulin resistance Strong appetite dysregulation or food noise Visceral fat or central weight gain PCOS-like metabolic features Weight-related joint pain or mobility limitations Elevated cardiometabolic risk markers This is why medical evaluation matters
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Inflammation Effects on Brain Glutamate in Depression: Mechanistic Considerations and Treatment Implications
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