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These results provide compelling evidence that semaglutide reduces ASCVD risk also in patients with obesity and established ASCVD but not T2D, laying groundwork for novel therapeutic strategies for the treatment of obesity in people with high risk for CV events
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Tirzepatide targets both GLP-1 and GIP receptors, making it more powerful for patients whose FTO rs9939609 or GIPR rs1800437 variants predispose them to appetite dysregulation
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