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As of 2026, Medicare Part D covers Wegovy only when prescribed for cardiovascular risk reduction in patients with established cardiovascular disease and obesity (the indication added after the SELECT trial in 2023)
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There are some non-M1 and non-M2 “restorative” type macrophages, which have both anti-inflammation and anti-fibrogenic features, highly express matrix metalloproteinase (MMP), and have a LY6C low , F4/80 + phenotype (Kazankov et al., 2019)
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