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If you've lost less than 5% body weight after 16 weeks at 10-15 mg with documented adherence, you may be a true non-responder

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Severe or persistent vomiting Signs of dehydration (excessive thirst, dark urine, dizziness) Severe abdominal pain Any symptoms of pancreatitis (pain radiating to your back, fever) Significant changes in bowel habits lasting more than a few days GLP-1 Medications in 2026: What’s New The GLP-1 landscape has expanded significantly entering 2026, offering patients more options and broader access than ever before