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However, a more recent RCT of 255 adults with nicotine dependence did not show any effect of adjunctive dulaglutide compared with standard of care (that is, behavioral counseling with varenicline) on cigarette abstinence over 12 weeks of treatment 117
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32 The primary outcome for the trial was the first occurrence of a major adverse cardiovascular event (death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke)
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